Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.36 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.36 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.36 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25624610 | 0.80 | CYP3A4 (0.42) | CYP3A4CYP2D6SIGMAR1KMT2AMEN1 | |
| SCHEMBL25613066 | 0.74 | CYP3A4 (0.46) | CYP3A4CYP2D6SIGMAR1KMT2AMEN1 | |
| SCHEMBL25624353 | 0.74 | SCN9A (0.30) | — | |
| SCHEMBL25613068 | 0.72 | CYP3A4 (0.45) | CYP3A4CYP2D6SIGMAR1KMT2AMEN1 | |
| SCHEMBL24714753 | 0.71 | GUCY1B2 (0.45) | CYP3A4CYP2D6SIGMAR1KMT2AMEN1 | |
| SCHEMBL25627478 | 0.70 | CYP2D6 (0.43) | CYP3A4CYP2D6SIGMAR1KMT2AMEN1 | |
| SCHEMBL25624526 | 0.70 | CYP2C19 (0.40) | CYP2D6ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL24351449 | 0.67 | SYK (0.45) | SIGMAR1KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL22962823 | 0.67 | SYK (0.48) | CYP3A4CYP2D6KMT2AMEN1ALDH1A1 | |
| SCHEMBL20347952 | 0.65 | KDM4E (0.55) | SIGMAR1ALDH1A1POLBSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159527-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON BIOSCIENCES, LTD. (CN) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159527-A1 | COMPOUNDS AS BCL-2 INHIBITORS | BCL2, BCL2L2, BCL2L1 | CYP3A4 3544/4885CYP2D6 3553/4885SIGMAR1 4271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.