Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23542760 | 0.89 | TSHR (0.42) | TSHRHPGDALDH1A1CYP3A4BBOX1 | |
| SCHEMBL35503 | 0.84 | TSHR (0.47) | TSHRHPGDALDH1A1CYP3A4BBOX1 | |
| SCHEMBL25625939 | 0.82 | TSHR (0.39) | TSHRBBOX1PSMD14PLA2G1BHSP90AA1 | |
| SCHEMBL23542761 | 0.82 | TSHR (0.43) | TSHRHPGDALDH1A1CYP3A4TP53 | |
| SCHEMBL18151515 | 0.82 | TSHR (0.49) | TSHRHPGDALDH1A1CYP3A4BBOX1 | |
| SCHEMBL16798842 | 0.82 | TSHR (0.49) | TSHRHPGDALDH1A1CYP3A4BBOX1 | |
| SCHEMBL16799361 | 0.82 | TSHR (0.49) | TSHRHPGDALDH1A1CYP3A4BBOX1 | |
| SCHEMBL16798967 | 0.82 | TSHR (0.49) | TSHRHPGDALDH1A1CYP3A4BBOX1 | |
| SCHEMBL16799249 | 0.82 | TSHR (0.49) | TSHRHPGDALDH1A1CYP3A4BBOX1 | |
| SCHEMBL16798961 | 0.82 | TSHR (0.49) | TSHRHPGDALDH1A1CYP3A4BBOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183515-A1 | COATING COMPOSITION, USE AND METHODS FOR MAKING A SUBSTRATE FROST RESISTANT | SOLVAY SA (BE) | 2023-06-15 | — | — | US | disclosed |