Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25177445 | 0.83 | USP2 (0.49) | USP2SMN1; SMN2RECQLMAPTALDH1A1 | |
| SCHEMBL4202170 | 0.81 | USP2 (0.53) | USP2SMN1; SMN2RECQLMAPTALDH1A1 | |
| SCHEMBL15920709 | 0.80 | USP2 (0.51) | USP2SMN1; SMN2RECQLMAPTALDH1A1 | |
| SCHEMBL15920689 | 0.80 | USP2 (0.51) | USP2SMN1; SMN2RECQLMAPTALDH1A1 | |
| SCHEMBL15920687 | 0.80 | USP2 (0.51) | USP2SMN1; SMN2RECQLMAPTALDH1A1 | |
| SCHEMBL15788105 | 0.77 | USP2 (0.51) | USP2SMN1; SMN2RECQLMAPTALDH1A1 | |
| SCHEMBL15788104 | 0.77 | USP2 (0.51) | USP2SMN1; SMN2RECQLMAPTALDH1A1 | |
| SCHEMBL30613708 | 0.77 | USP2 (0.51) | USP2SMN1; SMN2RECQLMAPTALDH1A1 | |
| SCHEMBL18909932 | 0.77 | USP2 (0.51) | USP2SMN1; SMN2RECQLMAPTALDH1A1 | |
| SCHEMBL13482004 | 0.77 | USP2 (0.51) | USP2SMN1; SMN2RECQLMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023097031-A1 | BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2023-06-01 | — | — | WO | disclosed |