Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 9/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 8/20 | 0.56 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 2/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.38 |
| ▸ | DGAT2 | Q96PD7 | 3/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23956976 | 1.00 | CHRM4 (0.56) | CHRM4CHRM2CCNT1CYP1A2CYP3A4 | |
| SCHEMBL30403430 | 1.00 | CHRM4 (0.56) | CHRM4CHRM2CCNT1CYP1A2CYP3A4 | |
| SCHEMBL25506910 | 0.86 | CHRM4 (0.56) | CHRM4CHRM2CCNT1CYP1A2CYP3A4 | |
| SCHEMBL25506605 | 0.86 | CHRM4 (0.56) | CHRM4CHRM2CCNT1CYP1A2CYP3A4 | |
| SCHEMBL30382812 | 0.86 | CHRM4 (0.56) | CHRM4CHRM2CCNT1CYP1A2CYP3A4 | |
| SCHEMBL23932221 | 0.86 | CHRM4 (0.62) | CHRM4CHRM2CYP1A2CYP3A4CYP2B6 | |
| SCHEMBL23932216 | 0.86 | CHRM4 (0.62) | CHRM4CHRM2CYP1A2CYP3A4CYP2B6 | |
| SCHEMBL23932218 | 0.86 | CHRM4 (0.62) | CHRM4CHRM2CYP1A2CYP3A4CYP2B6 | |
| SCHEMBL30456213 | 0.82 | HDAC1 (0.43) | CCNT1HDAC1HDAC2CDK9USP30 | |
| SCHEMBL23932280 | 0.81 | CHRM4 (0.67) | CHRM4CHRM2CYP1A2CYP3A4CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230183218-A1 | CONDENSED SUBSTITUTED HYDROPYRROLES AS ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 | VANDERBILT UNIVERSITY | 2023-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230183218-A1 | CONDENSED SUBSTITUTED HYDROPYRROLES AS ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 | CHRM3, CHRM2, CHRM4 | CHRM4 3/4885CHRM2 2/4885CCNT1 2164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.