⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21217097 | 0.88 | PIK3CD (0.31) | — | |
| SCHEMBL24992730 | 0.74 | PIK3CD (0.33) | — | |
| SCHEMBL22234670 | 0.74 | — | — | |
| SCHEMBL22843152 | 0.69 | — | — | |
| SCHEMBL18969303 | 0.69 | — | — | |
| SCHEMBL22259089 | 0.68 | — | — | |
| SCHEMBL24015523 | 0.67 | NAMPT (0.35) | — | |
| SCHEMBL10020689 | 0.67 | — | — | |
| SCHEMBL19506672 | 0.67 | NAMPT (0.30) | — | |
| SCHEMBL29325183 | 0.67 | PIK3CD (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116861-A1 | ANTI-DLL3 ANTIBODY AND PHARMACEUTICAL USE THEREOF, AND ANTIBODY-DRUG CONJUGATE CONTAINING ANTI-DLL3 ANTIBODY | 江苏恒瑞医药股份有限公司 | 2023-06-29 | — | — | WO | disclosed |
| WO-2023093845-A1 | CHIMERIC COMPOUND FOR TARGETED DEGRADATION OF ANDROGEN RECEPTOR PROTEIN, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 江苏恒瑞医药股份有限公司 | 2023-06-01 | — | — | WO | disclosed |