Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 4/20 | 0.41 |
| ▸ | BACE1 | P56817 | 4/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25273586 | 0.86 | MEN1 (0.46) | MEN1KMT2AACHEBACE1AURKA | |
| SCHEMBL25273634 | 0.80 | MEN1 (0.49) | MEN1KMT2AACHEBACE1AURKA | |
| SCHEMBL25631031 | 0.80 | HRH4 (0.44) | MEN1KMT2AACHEBACE1AURKA | |
| SCHEMBL25271281 | 0.79 | MEN1 (0.46) | MEN1KMT2AACHEBACE1AURKA | |
| SCHEMBL30456045 | 0.79 | MEN1 (0.46) | MEN1KMT2AACHEBACE1AURKA | |
| SCHEMBL25633484 | 0.79 | MEN1 (0.52) | MEN1KMT2A | |
| SCHEMBL25274694 | 0.77 | CYP2D6 (0.41) | MEN1KMT2ACYP1A2CYP2D6HTT | |
| SCHEMBL25631020 | 0.76 | CYP1A2 (0.42) | MEN1KMT2AACHEBACE1AURKA | |
| SCHEMBL25274939 | 0.74 | AKT1 (0.42) | MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL30455878 | 0.74 | MEN1 (0.43) | MEN1KMT2ACYP1A2EGFRKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107687-A1 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |