Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.57 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CKS1B | P61024 | 1/20 | 0.48 |
| ▸ | SKP1 | P63208 | 1/20 | 0.48 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | WNT3A | P56704 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14802434 | 0.89 | MAPT (0.59) | MAPTMEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL18673194 | 0.89 | MAPT (0.59) | MAPTMEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL25738496 | 0.88 | SMN1; SMN2 (0.61) | MAPTMEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL29913781 | 0.86 | SMN1; SMN2 (0.60) | MAPTMEN1KMT2ASMN1; SMN2TSHR | |
| Lithium Ion SCHEMBL20163132 | 0.86 | MEN1 (0.57) | MAPTMEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL14802410 | 0.86 | SMN1; SMN2 (0.60) | MAPTMEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL24649711 | 0.85 | SMN1; SMN2 (0.56) | MAPTMEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL22912831 | 0.85 | SMN1; SMN2 (0.65) | MAPTMEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL29020697 | 0.85 | MAPT (0.56) | MAPTMEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL29396475 | 0.85 | SMN1; SMN2 (0.65) | MAPTMEN1KMT2ASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023093845-A1 | CHIMERIC COMPOUND FOR TARGETED DEGRADATION OF ANDROGEN RECEPTOR PROTEIN, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 江苏恒瑞医药股份有限公司 | 2023-06-01 | — | — | WO | disclosed |