Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F13A1 | P00488 | 14/20 | 0.52 |
| ▸ | TGM2 | P21980 | 14/20 | 0.52 |
| ▸ | TGM6 | O95932 | 1/20 | 0.50 |
| ▸ | F13B | P05160 | 1/20 | 0.50 |
| ▸ | TGM1 | P22735 | 1/20 | 0.50 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.50 |
| ▸ | FAP | Q12884 | 3/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20353317 | 0.92 | F13A1 (0.55) | F13A1TGM2TGM6F13BTGM1 | |
| SCHEMBL20353378 | 0.92 | F13A1 (0.57) | F13A1TGM2TGM6F13BTGM1 | |
| SCHEMBL25636587 | 0.92 | F13A1 (0.57) | F13A1TGM2TGM6F13BTGM1 | |
| SCHEMBL20353406 | 0.92 | F13A1 (0.54) | F13A1TGM2TGM6F13BTGM1 | |
| SCHEMBL25636549 | 0.92 | F13A1 (0.54) | F13A1TGM2TGM6F13BTGM1 | |
| SCHEMBL25636581 | 0.91 | F13A1 (0.57) | F13A1TGM2TGM6F13BTGM1 | |
| SCHEMBL25636563 | 0.90 | F13A1 (0.65) | F13A1TGM2TGM6F13BTGM1 | |
| SCHEMBL20353314 | 0.90 | F13A1 (0.53) | F13A1TGM2TGM6F13BTGM1 | |
| SCHEMBL25636607 | 0.86 | F13A1 (0.49) | F13A1TGM2TGM6F13BTGM1 | |
| SCHEMBL25636530 | 0.83 | F13A1 (0.60) | F13A1TGM2TGM6F13BTGM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3405477-B1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2023-06-07 | — | — | EP | disclosed |