Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 9/20 | 0.48 |
| ▸ | DRD2 | P14416 | 8/20 | 0.48 |
| ▸ | HTR1A | P08908 | 7/20 | 0.48 |
| ▸ | DRD4 | P21917 | 6/20 | 0.48 |
| ▸ | HTR2A | P28223 | 6/20 | 0.48 |
| ▸ | HTR7 | P34969 | 5/20 | 0.48 |
| ▸ | DRD1 | P21728 | 4/20 | 0.48 |
| ▸ | DRD5 | P21918 | 4/20 | 0.48 |
| ▸ | HTR2C | P28335 | 3/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21477154 | 0.90 | DRD3 (0.49) | DRD3DRD2HTR1ADRD4HTR2A | |
| SCHEMBL20230946 | 0.77 | DRD3 (0.52) | DRD3DRD2HTR1ADRD4HTR2A | |
| SCHEMBL20128867 | 0.73 | DRD3 (0.48) | DRD3DRD2HTR1ADRD4HTR2A | |
| SCHEMBL11932478 | 0.73 | DRD4 (0.53) | DRD3DRD2DRD4HTR7DRD1 | |
| SCHEMBL21455986 | 0.73 | HRH3 (0.47) | HRH3 | |
| SCHEMBL21421582 | 0.71 | HRH3 (0.49) | DRD3DRD2DRD1DRD5ALDH1A1 | |
| SCHEMBL21421553 | 0.71 | AOC3 (0.37) | DRD3DRD2HTR1ADRD4HTR2A | |
| SCHEMBL26693415 | 0.70 | GBA1 (0.35) | ALDH1A1HRH3 | |
| SCHEMBL21421592 | 0.70 | SMN1; SMN2 (0.37) | SLC6A4SIGMAR1ALDH1A1 | |
| SCHEMBL20365422 | 0.69 | RET (0.47) | DRD3DRD2HTR1ADRD4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023097251-A1 | OLIGONUCLEOTIDE-CONTAINING TRANSCRIPTION FACTOR TARGETING CHIMERAS | YALE UNIVERSITY (US) | 2023-06-01 | — | — | WO | disclosed |