Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 20/20 | 0.71 |
| ▸ | BCR | P11274 | 1/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.67 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19544754 | 0.89 | ABL1 (0.73) | ABL1 | |
| SCHEMBL15393069 | 0.89 | ABL1 (0.87) | ABL1BCRKCNH2CRBN | |
| SCHEMBL25641409 | 0.89 | ABL1 (0.69) | ABL1 | |
| SCHEMBL19544765 | 0.87 | ABL1 (0.65) | ABL1 | |
| SCHEMBL17909940 | 0.86 | ABL1 (0.91) | ABL1 | |
| SCHEMBL19544760 | 0.85 | ABL1 (0.68) | ABL1 | |
| SCHEMBL19544730 | 0.85 | ABL1 (0.71) | ABL1 | |
| SCHEMBL19545243 | 0.84 | ABL1 (0.87) | ABL1BCRKCNH2CRBN | |
| SCHEMBL19544739 | 0.83 | ABL1 (0.65) | ABL1BCRKCNH2CRBN | |
| SCHEMBL20149006 | 0.83 | ABL1 (0.88) | ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114759-A2 | ABL INHIBITORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |