Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 2/20 | 0.35 |
| ▸ | METAP2 | P50579 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | AXL | P30530 | 7/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.30 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25640575 | 0.88 | CRBN (0.35) | BCL2METAP2MAPTAXLDDB1 | |
| SCHEMBL31165631 | 0.88 | BCL2 (0.43) | BCL2METAP2MAPTAXLBCL2L1 | |
| SCHEMBL30413769 | 0.88 | BCL2 (0.43) | BCL2METAP2MAPTAXLBCL2L1 | |
| SCHEMBL30415103 | 0.86 | BCL2 (0.45) | BCL2BCL2L1 | |
| SCHEMBL25640548 | 0.86 | BCL2 (0.45) | BCL2BCL2L1 | |
| SCHEMBL23943781 | 0.81 | BCL2 (0.36) | BCL2METAP2MAPTAXLBCL2L1 | |
| SCHEMBL23944122 | 0.76 | MAPT (0.38) | BCL2METAP2MAPTAXLBCL2L1 | |
| SCHEMBL23943774 | 0.76 | MEN1 (0.39) | BCL2METAP2MAPTAXLBCL2L1 | |
| SCHEMBL25640549 | 0.75 | BCL2 (0.37) | BCL2METAP2 | |
| SCHEMBL23925207 | 0.73 | AXL (0.46) | FFAR4AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104043-A1 | ANTI-APOPTOTIC PROTEIN BCL-2 INHIBITOR, PHARMACEUTICAL COMPOSITION AND USES THEREOF | 杭州和正医药有限公司 | 2023-06-15 | — | — | WO | disclosed |