Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | TACR2 | P21452 | 8/20 | 0.38 |
| ▸ | TACR1 | P25103 | 8/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1986735 | 0.84 | CNR1 (0.45) | CNR1CNR2TACR2TACR1 | |
| SCHEMBL1989951 | 0.81 | CNR1 (0.46) | CNR1CNR2TACR2TACR1 | |
| SCHEMBL12162983 | 0.78 | TACR2 (0.41) | CNR1CNR2TACR2TACR1HRH1 | |
| SCHEMBL1127599 | 0.76 | CNR1 (0.49) | CNR1CNR2TACR2TACR1 | |
| SCHEMBL476453 | 0.75 | CNR1 (0.42) | CNR1CNR2TACR2TACR1HRH1 | |
| SCHEMBL1846307 | 0.75 | CNR1 (0.40) | CNR1CNR2TACR2TACR1KCNH2 | |
| SCHEMBL1987560 | 0.75 | CNR1 (0.43) | CNR1CNR2TACR2TACR1HRH1 | |
| SCHEMBL1983795 | 0.73 | CNR1 (0.46) | CNR1CNR2TACR2TACR1 | |
| SCHEMBL1848918 | 0.73 | CNR1 (0.45) | CNR1CNR2TACR2TACR1KCNA5 | |
| SCHEMBL1990424 | 0.72 | CNR1 (0.51) | CNR1CNR2TACR2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283008-B1 | PYRROLE DERIVATIVES, PREPARATION OF SAME AND THERAPEUTIC APPLICATION THEREOF | SANOFI SA (FR) | 2011-11-02 | — | — | EP | disclosed |