Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 2/20 | 0.55 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.55 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.55 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | F7 | P08709 | 1/20 | 0.55 |
| ▸ | F3 | P13726 | 1/20 | 0.55 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.55 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.55 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.55 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.55 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.55 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.55 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | XDH | P47989 | 1/20 | 0.55 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.55 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenine SCHEMBL22748487 | 1.00 | PI4KA (0.55) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL15700 | 1.00 | PI4KA (0.55) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL1324561 | 0.99 | PI4KA (0.54) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL27518288 | 0.99 | PI4KA (0.54) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL11807683 | 0.99 | PI4KA (0.54) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL23531102 | 0.99 | PI4KA (0.54) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL7712108 | 0.99 | PI4KA (0.54) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL9274699 | 0.98 | PI4KA (0.52) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL8414755 | 0.96 | PI4KA (0.51) | PI4KAPI4K2BPI4K2API4KBLMNA | |
| Adenine SCHEMBL27371228 | 0.95 | PI4KA (0.50) | PI4KAPI4K2BPI4K2API4KBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011130385-A1 | BIOMARKERS FOR HEPATOCELLULAR CANCER | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC | 2011-10-20 | — | — | WO | disclosed |