⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3657022 | 0.61 | — | — | |
| SCHEMBL14076167 | 0.56 | — | — | |
| SCHEMBL1040248 | 0.56 | — | — | |
| SCHEMBL2508035 | 0.53 | — | — | |
| SCHEMBL19982748 | 0.52 | — | — | |
| SCHEMBL21170635 | 0.52 | — | — | |
| SCHEMBL9558214 | 0.51 | — | — | |
| SCHEMBL20967802 | 0.50 | — | — | |
| SCHEMBL22317589 | 0.49 | — | — | |
| SCHEMBL1325231 | 0.47 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2836590-A2 | METHODS FOR IMPROVING RESISTANCE TO SKELETAL MUSCLE FATIGUE | Cytokinetics, Incorporated (US) | 2015-02-18 | — | — | EP | disclosed |
| EP-2834269-A1 | METHODS FOR IMPROVING DIAPHRAGM FUNCTION | Cytokinetics, Inc. (US) | 2015-02-11 | — | — | EP | disclosed |
| WO-2013155262-A2 | METHODS FOR IMPROVING RESISTANCE TO SKELETAL MUSCLE FATIGUE | CYTOKINETICS, INC (US) | 2013-10-17 | — | — | WO | disclosed |
| WO-2013151938-A1 | METHODS FOR IMPROVING DIAPHRAGM FUNCTION | CYTOKINETICS, INC. (US) | 2013-10-10 | — | — | WO | disclosed |
| EP-2563365-A1 | CERTAIN AMINO-PYRIDAZINES, COMPOSITIONS THEREOF, AND METHODS OF THEIR USE | Cytokinetics, Inc. (US) | 2013-03-06 | — | — | EP | disclosed |
| EP-2560653-A1 | CERTAIN AMINO-PYRIMIDINES, COMPOSITIONS THEREOF, AND METHODS FOR THEIR USE | Cytokinetics, Inc. (US) | 2013-02-27 | — | — | EP | disclosed |
| EP-2560488-A1 | CERTAIN AMINO-PYRIDINES AND AMINO-TRIAZINES, COMPOSITIONS THEREOF, AND METHODS FOR THEIR USE | Cytokinetics, Inc. (US) | 2013-02-27 | — | — | EP | disclosed |
| WO-2011133888-A1 | CERTAIN AMINO-PYRIMIDINES, COMPOSITIONS THEREOF, AND METHODS FOR THEIR USE | CYTOKINETICS, INC. (US) | 2011-10-27 | — | — | WO | disclosed |
| WO-2011133882-A1 | CERTAIN AMINO-PYRIDAZINES, COMPOSITIONS THEREOF, AND METHODS OF THEIR USE | CYTOKINETICS, INC. (US) | 2011-10-27 | — | — | WO | disclosed |
| WO-2011133920-A1 | CERTAIN AMINO-PYRIDINES AND AMINO-TRIAZINES, COMPOSITIONS THEREOF, AND METHODS FOR THEIR USE | CYTOKINETICS, INC. (US) | 2011-10-27 | — | — | WO | disclosed |
| WO-2008008374-A2 | CCR2 INHIBITORS AND METHODS OF USE THEREOF | CHEMOCENTRYX, INC. (US) | 2008-01-17 | — | — | WO | disclosed |