Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKZF2 | Q9UKS7 | 8/20 | 0.57 |
| ▸ | CRBN | Q96SW2 | 8/20 | 0.56 |
| ▸ | IKZF3 | Q9UKT9 | 6/20 | 0.56 |
| ▸ | WIZ | O95785 | 1/20 | 0.53 |
| ▸ | IKZF1 | Q13422 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31076678 | 1.00 | IKZF2 (0.57) | IKZF2CRBNIKZF3WIZIKZF1 | |
| SCHEMBL31338412 | 0.90 | IKZF2 (0.57) | IKZF2CRBNIKZF3WIZIKZF1 | |
| SCHEMBL31338097 | 0.86 | IKZF2 (0.58) | IKZF2CRBNIKZF3IKZF1 | |
| SCHEMBL25647409 | 0.85 | CRBN (0.57) | CRBNIKZF3IKZF1 | |
| SCHEMBL31076953 | 0.85 | CRBN (0.57) | CRBNIKZF3IKZF1 | |
| SCHEMBL30458753 | 0.85 | CRBN (0.47) | IKZF2CRBNIKZF3 | |
| SCHEMBL25230219 | 0.85 | IKZF2 (0.58) | IKZF2CRBNIKZF3WIZIKZF1 | |
| SCHEMBL31337945 | 0.85 | CRBN (0.66) | IKZF2CRBNIKZF3WIZIKZF1 | |
| SCHEMBL31338231 | 0.85 | CRBN (0.66) | IKZF2CRBNIKZF3WIZIKZF1 | |
| SCHEMBL31338224 | 0.85 | IKZF2 (0.59) | IKZF2CRBNIKZF3WIZIKZF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116239566-A | E3 ubiquitin ligase ligand compound, protein degradation agent developed based on ligand compound and application thereof | 标新生物医药科技(上海)有限公司 | 2023-06-09 | — | — | CN | claimed |
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |