Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.82 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL182101 | 1.00 | BTK (0.82) | BTKKDM1AMAOBCTSKKMT2A | |
| SCHEMBL895759 | 1.00 | BTK (0.82) | BTKKDM1AMAOBCTSKKMT2A | |
| SCHEMBL13253521 | 1.00 | BTK (0.82) | BTKKDM1AMAOBCTSKKMT2A | |
| SCHEMBL2564638 | 1.00 | BTK (0.82) | BTKKDM1AMAOBCTSKKMT2A | |
| SCHEMBL1662045 | 1.00 | BTK (0.82) | BTKKDM1AMAOBCTSKKMT2A | |
| SCHEMBL1299320 | 1.00 | BTK (0.82) | BTKKDM1AMAOBCTSKKMT2A | |
| SCHEMBL540505 | 1.00 | BTK (0.82) | BTKKDM1AMAOBCTSKKMT2A | |
| SCHEMBL7486096 | 1.00 | BTK (0.82) | BTKKDM1AMAOBCTSKKMT2A | |
| SCHEMBL262171 | 0.91 | BTK (0.69) | BTKKDM1AMAOBCTSKKMT2A | |
| SCHEMBL30915791 | 0.91 | BTK (0.69) | BTKKDM1AMAOBCTSKKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117659022-A | Ureido substituted pyridine compound, pharmaceutical composition containing ureido substituted pyridine compound and medical application of ureido substituted pyridine compound | 苏州阿尔脉生物科技有限公司 | 2024-03-08 | — | — | CN | disclosed |
| WO-2023110936-A1 | REVERSIBLE MACROCYCLIC KINASE INHIBITORS | NETHERLANDS TRANSLATIONAL RESEARCH CENTER HOLDING B.V (NL) | 2023-06-22 | — | — | WO | disclosed |