⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25650150 | 0.83 | — | — | |
| SCHEMBL25650095 | 0.83 | — | — | |
| SCHEMBL25928596 | 0.78 | — | — | |
| SCHEMBL28607127 | 0.69 | — | — | |
| SCHEMBL25652302 | 0.69 | — | — | |
| SCHEMBL25650079 | 0.68 | — | — | |
| SCHEMBL27107939 | 0.68 | — | — | |
| SCHEMBL11662531 | 0.66 | — | — | |
| SCHEMBL11499586 | 0.65 | CYP3A4 (0.46) | — | |
| SCHEMBL11573684 | 0.64 | TDP1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4194553-A1 | MODIFIED SIRNA WITH REDUCED OFF-TARGET ACTIVITY | Tuojie Biotech (Shanghai) Co., Ltd. (CN) | 2023-06-14 | — | — | EP | disclosed |