Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | NNMT | P40261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10202992 | 0.77 | TAAR1 (0.41) | GCGRTAAR1LMNAXBP1SMN1; SMN2 | |
| SCHEMBL8293335 | 0.77 | GRIN2D (0.42) | LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL12304304 | 0.76 | HPGD (0.34) | TAAR1RIPK1 | |
| SCHEMBL13886438 | 0.74 | IDO1 (0.38) | GCGRTAAR1DAONOS3NOS1 | |
| SCHEMBL10193863 | 0.73 | TAAR1 (0.40) | GCGRTAAR1CNR1RIPK1 | |
| SCHEMBL14011594 | 0.73 | KDM4E (0.44) | LMNAL3MBTL1 | |
| SCHEMBL15736241 | 0.73 | TAAR1 (0.35) | TAAR1 | |
| SCHEMBL25215509 | 0.72 | TYR (0.46) | GCGRTAAR1RIPK1 | |
| SCHEMBL434483 | 0.72 | IDO1 (0.46) | GCGRSMN1; SMN2DAO | |
| SCHEMBL22605858 | 0.70 | GCGR (0.34) | GCGRLMNAXBP1SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114516-A2 | CELL-PERMEANT INHIBITORS OF VIRAL CYSTEINE PROTEASES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2023-06-22 | — | — | WO | disclosed |