⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25624436 | 0.86 | GRM4 (0.33) | — | |
| SCHEMBL25624363 | 0.74 | MAPK1 (0.31) | — | |
| SCHEMBL25650687 | 0.71 | KDR (0.31) | — | |
| SCHEMBL25624362 | 0.71 | CDK1 (0.34) | — | |
| SCHEMBL25625569 | 0.70 | FGFR1 (0.35) | — | |
| SCHEMBL25624434 | 0.70 | MERTK (0.35) | — | |
| SCHEMBL25626737 | 0.69 | LRRK2 (0.34) | — | |
| SCHEMBL25627364 | 0.69 | MAP3K7 (0.33) | — | |
| SCHEMBL25626807 | 0.69 | HTR2C (0.35) | — | |
| SCHEMBL25650927 | 0.68 | CDK1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159527-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON BIOSCIENCES, LTD. (CN) | 2023-05-25 | — | — | US | disclosed |