Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 20/20 | 0.56 |
| ▸ | DDB1 | Q16531 | 16/20 | 0.56 |
| ▸ | IKZF3 | Q9UKT9 | 4/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23066127 | 0.87 | CRBN (0.55) | CRBNDDB1IKZF3 | |
| SCHEMBL23066001 | 0.81 | DDB1 (0.74) | CRBNDDB1IKZF3 | |
| SCHEMBL23066097 | 0.78 | CRBN (0.63) | CRBNDDB1IKZF3 | |
| SCHEMBL23065972 | 0.75 | CRBN (0.73) | CRBNDDB1IKZF3 | |
| SCHEMBL22511857 | 0.75 | CRBN (0.73) | CRBNDDB1IKZF3 | |
| SCHEMBL23066007 | 0.74 | CRBN (0.65) | CRBNDDB1IKZF3 | |
| SCHEMBL3651084 | 0.72 | DDB1 (0.58) | CRBNDDB1IKZF3 | |
| SCHEMBL24132058 | 0.71 | DDB1 (0.73) | CRBNDDB1IKZF3 | |
| SCHEMBL20812400 | 0.71 | CRBN (1.00) | CRBNDDB1IKZF3 | |
| Hydrochloric Acid SCHEMBL22609484 | 0.70 | CRBN (0.97) | CRBNDDB1IKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159559-A1 | COMPOUND FOR INHIBITING AND INDUCING DEGRADATION OF EGFR KINASE | BEIJING TIDE PHARMACEUTICAL CO., LTD. (CN) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159559-A1 | COMPOUND FOR INHIBITING AND INDUCING DEGRADATION OF EGFR KINASE | EGFR, ERBB2, ERBB3 | CRBN 898/4885DDB1 2765/4885IKZF3 1670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.