Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 1.00 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 1.00 |
| ▸ | S1PR4 | O95977 | 2/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2567881 | 1.00 | S1PR1 (1.00) | S1PR1S1PR5S1PR4 | |
| SCHEMBL2562414 | 1.00 | S1PR1 (1.00) | S1PR1S1PR5S1PR4 | |
| SCHEMBL2567837 | 0.93 | S1PR1 (0.86) | S1PR1S1PR5S1PR4 | |
| SCHEMBL2565081 | 0.92 | S1PR1 (0.85) | S1PR1S1PR5S1PR4 | |
| SCHEMBL2564991 | 0.92 | S1PR1 (0.85) | S1PR1S1PR5S1PR4 | |
| SCHEMBL2566711 | 0.91 | S1PR1 (0.83) | S1PR1S1PR5S1PR4 | |
| SCHEMBL2567879 | 0.91 | S1PR1 (0.83) | S1PR1S1PR5S1PR4 | |
| SCHEMBL2564253 | 0.90 | S1PR1 (1.00) | S1PR1S1PR5S1PR4 | |
| SCHEMBL2562568 | 0.90 | S1PR1 (0.81) | S1PR1S1PR5S1PR4 | |
| SCHEMBL2562578 | 0.90 | S1PR1 (0.81) | S1PR1S1PR5S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222668-B1 | TETRAHYDROCYCLOPENTA[B]INDOL-3-YL CARBOXYLIC ACID DERIVATIVES USEFUL IN THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISORDERS | ARENA PHARM INC (US) | 2011-11-02 | — | — | EP | claimed |