Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | LPO | P22079 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19821657 | 0.80 | DAO (0.41) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL9389122 | 0.76 | DAO (0.45) | KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL32690180 | 0.72 | KDM4E (1.00) | KDM4EALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL21144481 | 0.68 | HPGD (0.67) | KDM4EALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL14079698 | 0.68 | PARP1 (0.40) | KDM4EALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL21341793 | 0.67 | KDM4E (0.43) | KDM4EALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL13757238 | 0.67 | GAA (0.37) | KDM4EALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL12499526 | 0.67 | RXFP1 (0.45) | RXFP1 | |
| SCHEMBL10005933 | 0.67 | HPGD (0.70) | KDM4EALDH1A1HPGDSMN1; SMN2HTT | |
| SCHEMBL824616 | 0.65 | PARP1 (0.43) | KDM4EALDH1A1HPGDSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230167065-A1 | NOVEL INTERMEDIATES AND SYNTHESIS FOR ENDOCHIN-LIKE QUINOLONE COMPOUNDS | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2023-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230167065-A1 | NOVEL INTERMEDIATES AND SYNTHESIS FOR ENDOCHIN-LIKE QUINOLONE COMPOUNDS | GALE, ENGASE, EPHX1 | KDM4E 2282/4885ALDH1A1 3471/4885HPGD 1286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.