Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 6/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2570283 | 0.92 | TSHR (0.34) | TSHRTP53KMT2ALMNAGAA | |
| SCHEMBL2567318 | 0.91 | TSHR (0.36) | TSHRTP53KMT2ALMNAGAA | |
| SCHEMBL2566162 | 0.89 | TSHR (0.35) | TSHRTP53KMT2ALMNAGAA | |
| SCHEMBL2997987 | 0.86 | TSHR (0.40) | TSHRTP53KMT2ALMNAGAA | |
| SCHEMBL2564410 | 0.85 | TSHR (0.41) | TSHRTP53KMT2ALMNAGAA | |
| SCHEMBL2568131 | 0.85 | TSHR (0.46) | TSHRTP53KMT2ALMNAGAA | |
| SCHEMBL2990546 | 0.84 | TSHR (0.40) | TSHRTP53KMT2ALMNAGAA | |
| SCHEMBL2566036 | 0.83 | TP53 (0.38) | TSHRTP53KMT2ALMNAGAA | |
| SCHEMBL2990464 | 0.83 | TSHR (0.35) | TSHRTP53KMT2ALMNAGAA | |
| SCHEMBL2569802 | 0.83 | TSHR (0.35) | TSHRTP53KMT2ALMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382218-A1 | DELTA-5-DESATURASE INHIBITORS | Takeda Pharmaceutical Company Limited (JP) | 2011-11-02 | — | — | EP | disclosed |
| WO-2010087467-A1 | DELTA-5-DESATURASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-05 | — | — | WO | disclosed |