Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 4/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 2/20 | 0.31 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.30 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25663489 | 0.98 | LIMK1 (0.35) | NPC1LIMK1CDK5CDK5R1RAB9A | |
| SCHEMBL25663157 | 0.88 | LIMK1 (0.35) | LIMK1CDK5CDK5R1HTR2CHRH4 | |
| SCHEMBL25663146 | 0.88 | CLK1 (0.40) | NPC1LIMK1RAB9APIK3CAEGFR | |
| SCHEMBL25663148 | 0.87 | LIMK1 (0.38) | NPC1LIMK1CDK5CDK5R1RAB9A | |
| SCHEMBL25663151 | 0.86 | LIMK1 (0.35) | NPC1LIMK1CDK5CDK5R1RAB9A | |
| SCHEMBL25663154 | 0.85 | LIMK1 (0.36) | LIMK1CDK5CDK5R1HTR2CHRH4 | |
| SCHEMBL25663158 | 0.85 | LIMK1 (0.37) | LIMK1CDK5CDK5R1HTR2CHRH4 | |
| SCHEMBL25663153 | 0.83 | NPC1 (0.38) | NPC1LIMK1CDK5CDK5R1RAB9A | |
| SCHEMBL25663152 | 0.82 | CYP1A2 (0.42) | NPC1LIMK1CDK5CDK5R1RAB9A | |
| SCHEMBL25663149 | 0.82 | LIMK1 (0.40) | LIMK1CDK5CDK5R1HTR2CHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230172057-A1 | HETEROCYCLIC COMPOUND CONTAINING HETEROATOM SUBSTITUTED FLUORENE AND OPTOELECTRONIC DEVICE | WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) | 2023-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230172057-A1 | HETEROCYCLIC COMPOUND CONTAINING HETEROATOM SUBSTITUTED FLUORENE AND OPTOELECTRONIC DEVICE | CHRM1, CHRM2, CHRM4 | NPC1 3859/4885LIMK1 1044/4885CDK5 1467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.