Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 14/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.49 |
| ▸ | KDR | P35968 | 3/20 | 0.49 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.49 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25662659 | 0.93 | EGFR (0.48) | EGFRERBB2KDREPHA2EPHB4 | |
| SCHEMBL25663424 | 0.91 | EGFR (0.51) | EGFRERBB2KDREPHA2EPHB4 | |
| SCHEMBL30420449 | 0.90 | EGFR (0.51) | EGFRERBB2KDREPHA2EPHB4 | |
| SCHEMBL25663391 | 0.90 | EGFR (0.51) | EGFRERBB2KDREPHA2EPHB4 | |
| SCHEMBL25217365 | 0.88 | EGFR (0.58) | EGFRKDR | |
| SCHEMBL25268005 | 0.88 | EGFR (0.58) | EGFRKDR | |
| SCHEMBL25215241 | 0.88 | EGFR (0.47) | EGFRERBB2KDREPHA2EPHB4 | |
| SCHEMBL25249827 | 0.88 | EGFR (0.47) | EGFRERBB2KDREPHA2EPHB4 | |
| SCHEMBL29382763 | 0.88 | EGFR (0.47) | EGFRERBB2KDREPHA2EPHB4 | |
| SCHEMBL25207968 | 0.86 | EGFR (0.48) | EGFRERBB2KDREPHA2EPHB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4194443-A1 | EFGR INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Abbisko Therapeutics Co., Ltd. (CN) | 2023-06-14 | — | — | EP | disclosed |