Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.58 |
| ▸ | KDR | P35968 | 5/20 | 0.58 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.49 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.48 |
| ▸ | DUS2 | Q9NX74 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29383961 | 1.00 | EGFR (0.58) | EGFRKDRERBB2ERBB3DUS2 | |
| SCHEMBL26055469 | 1.00 | EGFR (0.58) | EGFRKDRERBB2ERBB3DUS2 | |
| SCHEMBL25216865 | 0.91 | EGFR (0.60) | EGFRKDRERBB2ERBB3DUS2 | |
| SCHEMBL25270101 | 0.91 | EGFR (0.60) | EGFRKDRERBB2ERBB3DUS2 | |
| SCHEMBL25217365 | 0.90 | EGFR (0.58) | EGFRKDRERBB3DUS2 | |
| SCHEMBL25268005 | 0.90 | EGFR (0.58) | EGFRKDRERBB3DUS2 | |
| SCHEMBL25663542 | 0.88 | EGFR (0.48) | EGFRERBB2 | |
| SCHEMBL30429745 | 0.88 | EGFR (0.48) | EGFRERBB2 | |
| SCHEMBL26055468 | 0.88 | EGFR (0.48) | EGFRERBB2 | |
| SCHEMBL25371695 | 0.87 | EGFR (0.55) | EGFRKDRERBB2ERBB3DUS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4194443-A1 | EFGR INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Abbisko Therapeutics Co., Ltd. (CN) | 2023-06-14 | — | — | EP | disclosed |