⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23725527 | 0.91 | CD274 (0.33) | — | |
| SCHEMBL23725529 | 0.91 | CD274 (0.33) | — | |
| SCHEMBL30433392 | 0.91 | CD274 (0.33) | — | |
| SCHEMBL25664488 | 0.90 | — | — | |
| SCHEMBL23725564 | 0.83 | CD274 (0.33) | — | |
| SCHEMBL23725696 | 0.83 | CD274 (0.33) | — | |
| SCHEMBL25664240 | 0.82 | PDCD1 (0.30) | — | |
| SCHEMBL23726295 | 0.75 | CD274 (0.36) | — | |
| SCHEMBL25664242 | 0.72 | PDCD1 (0.32) | — | |
| SCHEMBL25664190 | 0.72 | CD274 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230143612-A1 | SUBSTITUTED 1,1'-BIPHENYL COMPOUNDS AND METHODS USING SAME | ARBUTUS BIOPHARMA CORP (US) | 2023-05-11 | — | — | US | disclosed |