Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 18/20 | 0.53 |
| ▸ | JAK1 | P23458 | 7/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | JAK2 | O60674 | 5/20 | 0.49 |
| ▸ | JAK3 | P52333 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30465847 | 0.93 | TYK2 (0.62) | TYK2JAK1CYP2C19JAK2 | |
| SCHEMBL25670933 | 0.93 | TYK2 (0.62) | TYK2JAK1CYP2C19JAK2 | |
| SCHEMBL25669827 | 0.84 | TYK2 (0.63) | TYK2JAK1CYP2C19JAK2 | |
| SCHEMBL30465841 | 0.81 | TYK2 (0.52) | TYK2JAK1CYP2C19JAK2 | |
| SCHEMBL25670653 | 0.81 | TYK2 (0.52) | TYK2JAK1CYP2C19JAK2 | |
| SCHEMBL25670928 | 0.80 | KAT2B (0.53) | TYK2JAK1CYP2C19JAK2 | |
| SCHEMBL26462376 | 0.77 | TYK2 (0.73) | TYK2JAK1CYP2C19JAK2 | |
| SCHEMBL31017330 | 0.75 | KAT2B (0.55) | TYK2JAK1 | |
| SCHEMBL30465878 | 0.75 | TYK2 (0.55) | TYK2JAK1JAK2 | |
| SCHEMBL25669919 | 0.75 | TYK2 (0.55) | TYK2JAK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109120-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2023-06-22 | — | — | WO | disclosed |