SCHEMBL25675893

SCHEMBL25675893

CC[C@@H]1CCSc2ccccc21

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 1/20 0.43
USP2 O75604 1/20 0.42
ALPL P05186 1/20 0.41
ALPI P09923 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
NPC1 O15118 1/20 0.39
POLB P06746 1/20 0.39
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21655317 1.00 KDM4C (0.43) KDM4CUSP2ALPLALPIMEN1
SCHEMBL15818455 0.81 KDM4C (0.43) KDM4CUSP2ALPLALPIMEN1
SCHEMBL12463825 0.81 SLC6A2 (0.38) KDM4CUSP2ALPLALPIMEN1
SCHEMBL5172771 0.79 KDM4C (0.44) KDM4CUSP2ALPLALPIMEN1
SCHEMBL24075123 0.79 USP2 (0.45) USP2ALPLALPIMEN1KMT2A
SCHEMBL12651544 0.79 USP2 (0.45) USP2ALPLALPIMEN1KMT2A
SCHEMBL12159553 0.79 USP2 (0.45) USP2ALPLALPIMEN1KMT2A
SCHEMBL5175333 0.77 KDM4C (0.43) KDM4CUSP2ALPLALPIMEN1
SCHEMBL8368454 0.76 KDM4C (0.51) KDM4CUSP2ALPLALPIMEN1
SCHEMBL660720 0.75 KDM4C (0.47) KDM4CUSP2MEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192671-A1 COMPOUNDS FOR THE TREATMENT OF SARS PURDUE RESEARCH FOUNDATION 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192671-A1 COMPOUNDS FOR THE TREATMENT OF SARS ACE2, ACE, SARS1 KDM4C 3346/4885USP2 342/4885ALPL 3714/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.