Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 16/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SNCA | P37840 | 1/20 | 0.50 |
| ▸ | LSS | P48449 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2567715 | 1.00 | APP (0.50) | APPMAPTSNCALSSKDM4E | |
| SCHEMBL2373608 | 0.87 | APP (0.55) | APPMAPTSNCAKMT2A | |
| SCHEMBL2373600 | 0.87 | APP (0.55) | APPMAPTSNCAKMT2A | |
| SCHEMBL32661374 | 0.86 | APP (0.46) | APPMAPTSNCALSS | |
| SCHEMBL14836106 | 0.85 | APP (0.53) | APPKMT2A | |
| SCHEMBL32661351 | 0.84 | APP (0.50) | APPMAPTSNCA | |
| SCHEMBL13863162 | 0.79 | APP (0.62) | APPMAPTSNCAKMT2A | |
| SCHEMBL12453261 | 0.78 | APP (0.55) | APPMAPTSNCA | |
| SCHEMBL12943443 | 0.78 | APP (0.55) | APPMAPTSNCA | |
| SCHEMBL2373639 | 0.77 | APP (0.55) | APPMAPTSNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2381967-B1 | SYNTHESIS OF 18F-RADIOLABELED STYRYLPYRIDINES FROM TOSYLATE PRECURSORS AND STABLE PHARMACEUTICAL COMPOSITIONS THEREOF | AVID RADIOPHARMACEUTICALS INC (US) | 2017-01-18 | — | — | EP | claimed |
| EP-2381967-A1 | SYNTHESIS OF 18F-RADIOLABELED STYRYLPYRIDINES FROM TOSYLATE PRECURSORS AND STABLE PHARMACEUTICAL COMPOSITIONS THEREOF | Avid Radiopharmaceuticals, Inc. (US) | 2011-11-02 | — | — | EP | claimed |
| WO-2010078370-A1 | SYNTHESIS OF 18F-RADIOLABELED STYRYLPYRIDINES FROM TOSYLATE PRECURSORS AND STABLE PHARMACEUTICAL COMPOSITIONS THEREOF | AVID RADIOPHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | claimed |
| US-20100172836-A1 | SYNTHESIS OF 18F-RADIOLABELED STYRYLPYRIDINES FROM TOSYLATE PRECURSORS AND STABLE PHARMACEUTICAL COMPOSITIONS THEREOF | AVID RADIOPHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | US | claimed |
| EP-2381967-B1 | SYNTHESIS OF 18F-RADIOLABELED STYRYLPYRIDINES FROM TOSYLATE PRECURSORS AND STABLE PHARMACEUTICAL COMPOSITIONS THEREOF | AVID RADIOPHARMACEUTICALS INC (US) | 2017-01-18 | — | — | EP | disclosed |
| EP-2381967-A1 | SYNTHESIS OF 18F-RADIOLABELED STYRYLPYRIDINES FROM TOSYLATE PRECURSORS AND STABLE PHARMACEUTICAL COMPOSITIONS THEREOF | Avid Radiopharmaceuticals, Inc. (US) | 2011-11-02 | — | — | EP | disclosed |
| WO-2010078370-A1 | SYNTHESIS OF 18F-RADIOLABELED STYRYLPYRIDINES FROM TOSYLATE PRECURSORS AND STABLE PHARMACEUTICAL COMPOSITIONS THEREOF | AVID RADIOPHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | WO | disclosed |
| US-20100172836-A1 | SYNTHESIS OF 18F-RADIOLABELED STYRYLPYRIDINES FROM TOSYLATE PRECURSORS AND STABLE PHARMACEUTICAL COMPOSITIONS THEREOF | AVID RADIOPHARMACEUTICALS, INC. (US) | 2010-07-08 | — | — | US | disclosed |