Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 15/20 | 0.54 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.54 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.54 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.54 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25220938 | 0.88 | PIK3CA (0.59) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR | |
| SCHEMBL30434311 | 0.88 | PIK3CA (0.59) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR | |
| SCHEMBL30322423 | 0.76 | PIK3CA (0.48) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR | |
| SCHEMBL30434662 | 0.76 | PIK3CA (0.48) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR | |
| SCHEMBL25220671 | 0.76 | PIK3CA (0.48) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR | |
| SCHEMBL30584279 | 0.76 | PIK3CA (0.57) | PIK3CAPIK3CBPIK3CDPIK3CGCYP1A1 | |
| SCHEMBL30322325 | 0.76 | PIK3CA (0.58) | PIK3CAPIK3CBMTORPRKDCPIK3C3 | |
| SCHEMBL30770735 | 0.74 | PIK3CA (0.59) | PIK3CAPIK3CBMTORPRKDCPIK3C3 | |
| SCHEMBL29202737 | 0.74 | PIK3CA (0.59) | PIK3CAPIK3CBMTORPRKDCPIK3C3 | |
| SCHEMBL30322557 | 0.74 | PIK3CA (0.57) | PIK3CAPIK3CBMTORPRKDCPIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104111-A1 | FUSED HETEROCYCLIC COMPOUNDS AS PI3KALPHA INHIBITORS | NANJING ZENSHINE PHARMACEUTICALS CO., LTD. (CN) | 2023-06-15 | — | — | WO | disclosed |