SCHEMBL256777

SCHEMBL256777

[O-][S+]1CCOC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2182211 0.81
SCHEMBL2181008 0.79
SCHEMBL256058 0.79
SCHEMBL2180877 0.77
SCHEMBL2621586 0.69
SCHEMBL5213752 0.65
Fluoride SCHEMBL27648634 0.52
Oxirane SCHEMBL973217 0.46
Oxirane SCHEMBL3587 0.46
Oxirane SCHEMBL8094696 0.46 TTR (0.83)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 635 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5654441-A Synthesis of 1,3-oxathiolane sulfoxide compounds UNIROYAL CHEMICAL LTD./LTEE (CA) 1997-08-05 US claimed
US-4152334-A Process for preparing 5,6-dihydro-2-methyl-1,4-oxathiin derivatives LEE WHA S 1979-05-01 US claimed
WO-2024126453-A1 NEW SUBSTITUTED INDOLE-2-CARBOXAMIDES AS PHGDH INHIBITORS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2024-06-20 WO disclosed
WO-2024088991-A1 HETEROCYCLIC COMPOUNDS CAPABLE OF ACTIVATING STING BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2024-05-02 WO disclosed
WO-2024089155-A1 HETEROCYCLIC COMPOUNDS AS STING ANTAGONISTS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2024-05-02 WO disclosed
WO-2024089006-A1 HETEROCYCLIC COMPOUNDS CAPABLE OF ACTIVATING STING BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2024-05-02 WO disclosed
WO-2023073641-A9 ANTHELMINTIC PYRROLOPYRIDAZINE COMPOUNDS BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2024-02-29 WO disclosed
US-20230374021-A1 [1,3]DIAZINO[5,4-d]PYRIMIDINES AS HER2 INHIBITORS BOEHRINGER INGELHEIM INT (DE) 2023-11-23 US disclosed
US-20230374021-A1 [1,3]DIAZINO[5,4-d]PYRIMIDINES AS HER2 INHIBITORS BOEHRINGER INGELHEIM INT (DE) 2023-11-23 US disclosed
US-11814380-B2 Benzylamino substituted pyridopyrimidinones and derivatives as SOS1 inhibitors BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2023-11-14 US disclosed
US-20230355638-A1 Cyclopentathiophene Carboxamide Derivatives as Platelet Activating Factor Receptor Antagonists BOEHRINGER INGELHEIM INT (DE) 2023-11-09 US disclosed
US-5081143-A Fungicidal oxathiin azoles UNIROYAL CHEMICAL COMPANY, INC. (US) 1992-01-14 US disclosed
WO-1991005782-A1 FUNGICIDAL OXATHIIN AZOLES UNIROYAL CHEMICAL COMPANY, INC. (US) 1991-05-02 WO disclosed
US-4966910-A Fungicidal oxathiin azoles UNIROYAL CHEMICAL COMPANY, INC. (US) 1990-10-30 US disclosed
US-4619924-A BACTERICIDES PFIZER INC. (US) 1986-10-28 US disclosed
EP-0130025-A1 2-Alkylthiopenem derivatives PFIZER INC. (US) 1985-01-02 EP disclosed
EP-0010843-B1 METHOD OF MAKING 5,6-DIHYDRO-2-METHYL-N-PHENYL-1,4-OXATHIIN-3-CARBOXAMIDE UNIROYAL LTD. (CA) 1983-11-09 EP disclosed
EP-0042182-A2 Method of making 5,6-dihydro-2-methyl-N-phenyl-1,4-oxathiin-3-carboxamide UNIROYAL LTD. (CA) 1981-12-23 EP disclosed
US-4247707-A CATALYTIC LIQUID-PHASE OXIDATION OF 2-METHYL-N-PHENYL-1,3-OXATHIOLANE-2-ACETAMIDE; THEN CATALYTIC THERMAL RING EXPANSION UNIROYAL CHEMICAL CO./UNIROYAL CHEMICAL CLE. (CA) 1981-01-27 US disclosed
US-4182716-A Method of making 5,6-dihydro-2-methyl-N-phenyl-1,4-oxathiin-3-carboxamide UNIROYAL, LTD. (CA) 1980-01-08 US disclosed