Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4219818 | 0.87 | SMN1; SMN2 (0.49) | SMN1; SMN2HSD17B10PKMATMCA12 | |
| SCHEMBL21880026 | 0.85 | SMN1; SMN2 (0.55) | SMN1; SMN2HSD17B10PKMATMCA12 | |
| SCHEMBL30720842 | 0.85 | SMN1; SMN2 (0.47) | SMN1; SMN2HSD17B10PKMATMCA12 | |
| SCHEMBL31505752 | 0.85 | SMN1; SMN2 (0.47) | SMN1; SMN2HSD17B10PKMATMCA12 | |
| SCHEMBL15415823 | 0.85 | SMN1; SMN2 (0.47) | SMN1; SMN2HSD17B10PKMATMCA12 | |
| SCHEMBL12457570 | 0.82 | HSP90AB1 (0.41) | HSD17B10ATMKDM4EGAAALDH1A1 | |
| SCHEMBL7890254 | 0.82 | CA12 (0.51) | SMN1; SMN2HSD17B10PKMATMCA12 | |
| SCHEMBL25096492 | 0.82 | SMN1; SMN2 (0.45) | SMN1; SMN2HSD17B10PKMATMCA12 | |
| SCHEMBL21880024 | 0.82 | SMN1; SMN2 (0.45) | SMN1; SMN2HSD17B10PKMATMCA12 | |
| SCHEMBL29104397 | 0.81 | CA12 (0.50) | SMN1; SMN2HSD17B10PKMATMCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024137329-A1 | METHODS FOR THE SYNTHESIS OF COMPLEMENT FACTOR D INHIBITORS AND INTERMEDIATES THEREOF | ALEXION PHARMACEUTICALS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |
| WO-2023114200-A2 | METHODS FOR THE SYNTHESIS OF COMPLEMENT FACTOR D INHIBITORS AND INTERMEDIATES THEREOF | ALEXION PHARMACEUTICALS, INC. (US) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023114198-A2 | METHODS FOR THE SYNTHESIS OF COMPLEMENT FACTOR D INHIBITORS | ALEXION PHARMACEUTICALS, INC. (US) | 2023-06-22 | — | — | WO | disclosed |