Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 19/20 | 0.58 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.56 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.56 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.56 |
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
| ▸ | PRKDC | P78527 | 1/20 | 0.54 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31516558 | 0.95 | PIK3CA (0.61) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR | |
| SCHEMBL25682966 | 0.94 | PIK3CA (0.55) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR | |
| SCHEMBL25685461 | 0.92 | PIK3CA (0.69) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR | |
| SCHEMBL30434461 | 0.90 | PIK3CA (0.70) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR | |
| SCHEMBL25674035 | 0.90 | PIK3CA (0.70) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR | |
| SCHEMBL25683208 | 0.89 | PIK3CA (0.53) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR | |
| SCHEMBL25685464 | 0.88 | PIK3CA (0.63) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR | |
| SCHEMBL29202712 | 0.88 | PIK3CA (0.51) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR | |
| SCHEMBL25682967 | 0.88 | PIK3CA (0.51) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR | |
| SCHEMBL25683183 | 0.88 | PIK3CA (0.56) | PIK3CAPIK3CBPIK3CDPIK3CGMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104111-A1 | FUSED HETEROCYCLIC COMPOUNDS AS PI3KALPHA INHIBITORS | NANJING ZENSHINE PHARMACEUTICALS CO., LTD. (CN) | 2023-06-15 | — | — | WO | disclosed |