Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 18/20 | 0.64 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467182 | 0.81 | HRH4 (0.58) | HRH4HRH3KCNH2 | |
| SCHEMBL3467181 | 0.81 | HRH4 (0.58) | HRH4HRH3KCNH2 | |
| SCHEMBL1775385 | 0.81 | HRH4 (0.67) | HRH4HRH3KCNH2 | |
| SCHEMBL1774659 | 0.80 | HRH4 (0.77) | HRH4HRH3KCNH2NUDT1 | |
| SCHEMBL603024 | 0.80 | HRH4 (0.49) | HRH4HRH3 | |
| SCHEMBL603023 | 0.80 | HRH4 (0.49) | HRH4HRH3 | |
| SCHEMBL1774201 | 0.78 | HRH4 (0.66) | HRH4HRH3KCNH2NUDT1 | |
| SCHEMBL5152060 | 0.78 | HRH4 (0.73) | HRH4HRH3KCNH2NUDT1 | |
| SCHEMBL1774257 | 0.78 | HRH4 (0.73) | HRH4HRH3KCNH2NUDT1 | |
| SCHEMBL12605095 | 0.78 | HRH4 (0.73) | HRH4HRH3KCNH2NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382013-A1 | SELECTIVE HISTAMINE H4 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF VESTIBULAR DISORDERS. | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2011-11-02 | — | — | EP | disclosed |
| WO-2010072829-A1 | SELECTIVE HISTAMINE H4 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF VESTIBULAR DISORDERS. | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2010-07-01 | — | — | WO | disclosed |