Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2567965 | 0.95 | CNR1 (0.53) | CNR1CYP2C19GAALMNAUSP2 | |
| SCHEMBL1127743 | 0.95 | CNR1 (0.53) | CNR1CYP2C19GAALMNAUSP2 | |
| SCHEMBL1986400 | 0.95 | CNR1 (0.53) | CNR1CYP2C19GAALMNAUSP2 | |
| SCHEMBL1989137 | 0.95 | CNR1 (0.53) | CNR1CYP2C19GAALMNAUSP2 | |
| SCHEMBL1989851 | 0.94 | CNR1 (0.53) | CNR1CYP2C19GAALMNAUSP2 | |
| SCHEMBL1128279 | 0.93 | CNR1 (0.55) | CNR1CYP2C19GAALMNAUSP2 | |
| SCHEMBL1988428 | 0.92 | CNR1 (0.53) | CNR1CYP2C19GAALMNAUSP2 | |
| SCHEMBL1986717 | 0.91 | CNR1 (0.52) | CNR1CYP2C19GAALMNAUSP2 | |
| SCHEMBL1985670 | 0.90 | CNR1 (0.67) | CNR1CYP2C19GAALMNAUSP2 | |
| SCHEMBL2560778 | 0.90 | CNR1 (0.53) | CNR1CYP2C19GAALMNAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383666-B2 | Pyrrole derivatives, preparation of same and therapeutic application thereof | SANOFI (FR) | 2013-02-26 | — | — | US | disclosed |
| EP-2283008-B1 | PYRROLE DERIVATIVES, PREPARATION OF SAME AND THERAPEUTIC APPLICATION THEREOF | SANOFI SA (FR) | 2011-11-02 | — | — | EP | disclosed |