Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.55 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | DRD4 | P21917 | 7/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | CCR3 | P51677 | 1/20 | 0.51 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.51 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.50 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17409811 | 0.87 | SMYD3 (0.70) | SMYD3KMT2ACARM1PRMT6SIGMAR1 | |
| SCHEMBL10263884 | 0.84 | SMYD3 (0.86) | SMYD3KMT2A | |
| SCHEMBL24529101 | 0.81 | SMYD3 (0.78) | SMYD3KMT2A | |
| SCHEMBL21257402 | 0.81 | SMYD3 (0.78) | SMYD3KMT2A | |
| SCHEMBL17409822 | 0.78 | SMYD3 (0.72) | SMYD3KMT2A | |
| SCHEMBL21489836 | 0.78 | SMYD3 (1.00) | SMYD3 | |
| SCHEMBL19701229 | 0.78 | SMYD3 (1.00) | SMYD3 | |
| SCHEMBL24529100 | 0.78 | SMYD3 (0.72) | SMYD3 | |
| SCHEMBL22098507 | 0.77 | SMYD3 (0.74) | SMYD3KMT2A | |
| SCHEMBL24529113 | 0.76 | SMYD3 (0.66) | SMYD3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023110700-A1 | DIHYDROFUROPYRIDINE DERIVATIVES AS RHO-KINASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2023-06-22 | — | — | WO | disclosed |