Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 15/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2597588 | 0.90 | MTOR (0.52) | MTORPIK3CAPIK3R1 | |
| SCHEMBL2567788 | 0.90 | MTOR (0.49) | MTORPIK3CAPIK3R1 | |
| SCHEMBL3049847 | 0.80 | MTOR (0.43) | MTORPIK3CAPIK3R1 | |
| SCHEMBL2597501 | 0.79 | MTOR (0.62) | MTORPIK3CAPIK3R1 | |
| Hydrochloric Acid SCHEMBL2566544 | 0.79 | MTOR (0.42) | MTORPIK3CAPIK3R1 | |
| SCHEMBL1359184 | 0.77 | MTOR (0.65) | MTORPIK3CAPIK3R1 | |
| SCHEMBL2597653 | 0.75 | MTOR (0.59) | MTORPIK3CAPIK3R1 | |
| SCHEMBL2597510 | 0.74 | MTOR (0.57) | MTORPIK3CAPIK3R1 | |
| SCHEMBL2597542 | 0.74 | MTOR (0.57) | MTORPIK3CAPIK3R1 | |
| SCHEMBL2597633 | 0.74 | MTOR (0.57) | MTORPIK3CAPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382207-A2 | PI3K/MTOR KINASE INHIBITORS | Xcovery Holding Company LLC (US) | 2011-11-02 | — | — | EP | claimed |
| WO-2010056320-A2 | PI3K/MTOR KINASE INHIBITORS | TYROGENEX, INC. (US) | 2010-05-20 | — | — | WO | claimed |