SCHEMBL2568837

SCHEMBL2568837

CCC1=Cc2c(-c3ccc(C(C)(C)C)cc3)cccc2C1[Hf](C1C(CC)=Cc2c(-c3ccc(C(C)(C)C)cc3)cccc21)[SiH](C)C

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.30
CREBBP Q92793 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16628775 0.91
SCHEMBL27567467 0.86 BRD4 (0.32) BRD4CREBBP
SCHEMBL2235436 0.84 BRD4 (0.32) BRD4CREBBP
SCHEMBL7182715 0.83 BRD4 (0.30) BRD4CREBBP
Hydrochloric Acid SCHEMBL2232394 0.83 BRD4 (0.31) BRD4CREBBP
SCHEMBL28755323 0.81 BRD4 (0.32) BRD4CREBBP
SCHEMBL12475618 0.81 BRD4 (0.30) BRD4CREBBP
Dimethylamine SCHEMBL5703379 0.81
SCHEMBL22411219 0.79
SCHEMBL7035276 0.79 BRD4 (0.33) BRD4CREBBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2134801-B1 ADHESIVE POLYMER COMPOSITION BASELL POLYOLEFINE GMBH (DE) 2011-11-02 EP disclosed
EP-2236577-A2 Polyethylene composition Basell Polyolefine GmbH (DE) 2010-10-06 EP disclosed