Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 15/20 | 0.65 |
| ▸ | HTR2A | P28223 | 13/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24143180 | 0.94 | HTR2C (0.65) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL24143058 | 0.86 | HTR2C (0.54) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL13970610 | 0.81 | HTR2C (0.80) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL24143095 | 0.79 | HTR2C (0.63) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL26674202 | 0.79 | HTR2C (0.63) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL15307684 | 0.79 | HTR2C (0.78) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL23927873 | 0.79 | HTR2C (0.55) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29780337 | 0.79 | HTR2C (0.55) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL23927872 | 0.79 | HTR2C (0.55) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL21872466 | 0.79 | HTR2C (0.54) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632443-B1 | ANTI-TUMOR EFFECT POTENTIATOR USING A BIPHENYL COMPOUND | TAIHO PHARMACEUTICAL CO LTD (JP) | 2023-06-07 | — | — | EP | disclosed |