Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 12/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.45 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25684232 | 0.84 | TLR8 (0.54) | TLR8TLR7 | |
| SCHEMBL12908804 | 0.78 | TLR8 (0.53) | TLR8TLR7 | |
| SCHEMBL25681750 | 0.78 | TLR8 (0.48) | TLR8TLR7 | |
| SCHEMBL25688388 | 0.77 | TLR8 (0.53) | TLR8TLR7 | |
| SCHEMBL1588858 | 0.76 | TLR8 (0.71) | TLR8TLR7 | |
| SCHEMBL10044374 | 0.74 | TLR8 (0.53) | TLR8TLR7 | |
| SCHEMBL21841734 | 0.73 | TLR8 (0.54) | TLR8TLR7 | |
| SCHEMBL12908673 | 0.73 | TLR8 (0.59) | TLR8TLR7 | |
| SCHEMBL12619381 | 0.73 | TLR8 (0.59) | TLR8TLR7 | |
| SCHEMBL21841694 | 0.73 | TLR8 (0.53) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109944-A1 | TLR MODULATOR AND USE THEREOF | 映恩生物制药（苏州）有限公司 | 2023-06-22 | — | — | WO | disclosed |