Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 2/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.52 |
| ▸ | PIM1 | P11309 | 1/20 | 0.52 |
| ▸ | PRKACA | P17612 | 1/20 | 0.52 |
| ▸ | CDK7 | P50613 | 1/20 | 0.52 |
| ▸ | CDK9 | P50750 | 1/20 | 0.52 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.52 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.52 |
| ▸ | GSK3A | P49840 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | PTK2 | Q05397 | 9/20 | 0.51 |
| ▸ | KDR | P35968 | 2/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.49 |
| ▸ | TYK2 | P29597 | 1/20 | 0.49 |
| ▸ | JAK3 | P52333 | 1/20 | 0.49 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.49 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.49 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25692158 | 0.88 | PTK2 (0.63) | CDC7ROCK2MAP4K4PIM1PRKACA | |
| SCHEMBL25692191 | 0.87 | GSK3A (0.69) | CDC7ROCK2MAP4K4PIM1PRKACA | |
| SCHEMBL25692320 | 0.83 | AURKA (0.44) | CDC7MAP4K4PIM1HIPK2IRAK4 | |
| SCHEMBL24752270 | 0.82 | PTK2 (0.58) | CDC7ROCK2MAP4K4PIM1PRKACA | |
| SCHEMBL30001799 | 0.82 | PTK2 (0.58) | CDC7ROCK2MAP4K4PIM1PRKACA | |
| SCHEMBL25692540 | 0.81 | MAPK8 (0.64) | CDC7ROCK2MAP4K4PIM1PRKACA | |
| SCHEMBL25692215 | 0.78 | PTK2 (0.58) | PTK2KDRJAK2NTRK1TYK2 | |
| SCHEMBL25692119 | 0.78 | PTK2 (0.54) | CDC7ROCK2MAP4K4PIM1PRKACA | |
| SCHEMBL25692237 | 0.77 | MAPK3 (0.47) | CDC7ROCK2MAP4K4PIM1PRKACA | |
| SCHEMBL25692657 | 0.77 | AURKA (0.54) | CDC7ROCK2MAP4K4PIM1PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023121251-A1 | EGFR AND HDAC DUAL INHIBITOR COMPOUNDS AND MEDICAL USE THEREOF | 한국원자력의학원 | 2023-06-29 | — | — | WO | disclosed |