Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 4/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.62 |
| ▸ | THPO | P40225 | 1/20 | 0.62 |
| ▸ | APP | P05067 | 6/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | CYP2E1 | P05181 | 3/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.47 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL25239520 | 0.98 | BLM (0.64) | CYP2C19CYP1A2CYP3A4CYP2C9THPO | |
| SCHEMBL6449000 | 0.89 | CYP2C19 (0.75) | CYP2C19CYP1A2CYP3A4CYP2C9THPO | |
| SCHEMBL12568364 | 0.80 | CYP2C19 (0.50) | CYP2C19CYP1A2CYP3A4CYP2C9THPO | |
| SCHEMBL7038938 | 0.78 | CYP2C19 (0.60) | CYP2C19CYP1A2CYP3A4CYP2C9THPO | |
| SCHEMBL22122003 | 0.78 | CYP2C19 (0.60) | CYP2C19CYP1A2CYP3A4CYP2C9THPO | |
| SCHEMBL3451115 | 0.78 | CYP2C19 (0.60) | CYP2C19CYP1A2CYP3A4CYP2C9THPO | |
| SCHEMBL2080824 | 0.78 | CYP2C19 (0.60) | CYP2C19CYP1A2CYP3A4CYP2C9THPO | |
| SCHEMBL7573145 | 0.78 | CYP2C19 (0.60) | CYP2C19CYP1A2CYP3A4CYP2C9THPO | |
| SCHEMBL11459291 | 0.78 | APP (0.59) | CYP2C19CYP1A2CYP3A4CYP2C9THPO | |
| SCHEMBL12523558 | 0.78 | CYP2C19 (0.60) | CYP2C19CYP1A2CYP3A4CYP2C9THPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023113457-A1 | NOVEL COMPOUND FOR DEGRADING TARGET PROTEIN OR POLYPEPTIDE BY USING POLYUBIQUITINATION | (주)프레이저테라퓨틱스 | 2023-06-22 | — | — | WO | disclosed |
| WO-2023113456-A1 | NOVEL COMPOUND FOR DEGRADING TARGET PROTEIN OR POLYPEPTIDE BY USING POLYUBIQUITINATION | (주)프레이저테라퓨틱스 | 2023-06-22 | — | — | WO | disclosed |