SCHEMBL25694

SCHEMBL25694

COC1CCc2cc(Br)ccc21

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 5/20 0.47
SRD5A1 P18405 1/20 0.46
IDO1 P14902 2/20 0.37
KDM1A O60341 2/20 0.37
CAMK2A Q9UQM7 1/20 0.36
HTR2A P28223 2/20 0.36
HTR2C P28335 2/20 0.36
HTR2B P41595 1/20 0.36
ADRA2A P08913 1/20 0.34
PNMT P11086 1/20 0.34
ADRA2B P18089 1/20 0.34
ADRA2C P18825 1/20 0.34
SLC6A2 P23975 1/20 0.34
CYP19A1 P11511 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17028714 0.90 SRD5A1 (0.40) SLC6A4SRD5A1IDO1KDM1ACAMK2A
SCHEMBL6482195 0.87 HTR2A (0.47) SLC6A4SRD5A1IDO1HTR2AHTR2C
SCHEMBL14567304 0.82 SLC6A4 (0.44) SLC6A4SRD5A1IDO1KDM1ACAMK2A
SCHEMBL19125887 0.81 KDM1A (0.46) SLC6A4SRD5A1KDM1AHTR2AHTR2C
SCHEMBL27787753 0.79 SRD5A1 (0.44) SLC6A4SRD5A1CAMK2A
SCHEMBL22547324 0.79 SRD5A1 (0.46) SLC6A4SRD5A1IDO1ADRA2APNMT
SCHEMBL31394210 0.78 SLC6A4 (0.47) SLC6A4SRD5A1IDO1KDM1ACAMK2A
SCHEMBL14969006 0.77 SLC6A4 (0.46) SLC6A4SRD5A1IDO1SLC6A2
SCHEMBL227332 0.77 SLC6A4 (0.41) SLC6A4SRD5A1IDO1KDM1ACAMK2A
SCHEMBL13487595 0.76 SRD5A1 (0.47) SLC6A4SRD5A1KDM1ACAMK2AHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025049746-A1 COMPOSITIONS COMPRISING WERNER SYNDROME HELICASE INHIBITORS AND METHODS OF USING THE SAME EIKON THERAPEUTICS, INC. (US) 2025-03-06 WO disclosed
WO-2012026403-A1 CONDENSED RING COMPOUND 日本曹達株式会社 (JP) 2012-03-01 WO disclosed
WO-2006065809-A2 HETEROATOM BRIDGED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-06-22 WO disclosed