Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A3 | P48764 | 14/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13286035 | 1.00 | SLC9A3 (0.67) | SLC9A3 | |
| SCHEMBL17576927 | 0.94 | SLC9A3 (0.59) | SLC9A3 | |
| SCHEMBL20953590 | 0.89 | SLC9A3 (0.71) | SLC9A3 | |
| SCHEMBL16883963 | 0.86 | SLC9A3 (0.60) | SLC9A3 | |
| SCHEMBL24973106 | 0.86 | SLC9A3 (0.79) | SLC9A3 | |
| SCHEMBL19661896 | 0.86 | SLC9A3 (0.76) | SLC9A3 | |
| SCHEMBL2568722 | 0.85 | SLC9A3 (0.49) | SLC9A3 | |
| SCHEMBL2568719 | 0.85 | SLC9A3 (0.49) | SLC9A3 | |
| SCHEMBL2573261 | 0.85 | SLC9A3 (0.81) | SLC9A3 | |
| SCHEMBL2575656 | 0.84 | SLC9A3 (0.79) | SLC9A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3921327-A1 | GLYCYRRHETINIC ACID DERIVATIVES FOR USE IN TREATING HYPERKALEMIA | Ardelyx, Inc. (US) | 2021-12-15 | — | — | EP | disclosed |
| WO-2020163642-A1 | GLYCYRRHETINIC ACID DERIVATIVES FOR USE IN TREATING HYPERKALEMIA | ARDELYX, INC. (US) | 2020-08-13 | — | — | WO | disclosed |
| WO-2018129556-A1 | COMPOUNDS AND METHODS FOR INHIBITING NHE-MEDIATED ANTIPORT IN THE TREATMENT OF DISORDERS ASSOCIATED WITH FLUID RETENTION OR SALT OVERLOAD AND GASTROINTESTINAL TRACT DISORDERS | ARDELYX, INC. (US) | 2018-07-12 | — | — | WO | disclosed |
| EP-2384318-A2 | COMPOUNDS AND METHODS FOR INHIBITING NHE-MEDIATED ANTIPORT IN THE TREATMENT OF DISORDERS ASSOCIATED WITH FLUID RETENTION OR SALT OVERLOAD AND GASTROINTESTINAL TRACT DISORDERS | Ardelyx, Inc. (US) | 2011-11-09 | — | — | EP | disclosed |