Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | CPB1 | P15086 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | AKT1 | P31749 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4083289 | 0.85 | KMT2A (0.53) | KMT2AL3MBTL1KDM1AMAOBCA12 | |
| SCHEMBL23153407 | 0.85 | KMT2A (0.53) | KMT2AL3MBTL1KDM1AMAOBCA12 | |
| SCHEMBL765249 | 0.85 | KMT2A (0.53) | KMT2AL3MBTL1KDM1AMAOBCA12 | |
| SCHEMBL29761166 | 0.85 | KMT2A (0.56) | KMT2AL3MBTL1KDM1AMAOBCA12 | |
| SCHEMBL3208730 | 0.81 | KMT2A (0.52) | KMT2AL3MBTL1KDM1AMAOBCA12 | |
| SCHEMBL5694937 | 0.80 | KMT2A (0.58) | KMT2AL3MBTL1KDM1AMAOBCA12 | |
| SCHEMBL4266535 | 0.80 | KMT2A (0.58) | KMT2AL3MBTL1KDM1AMAOBCA12 | |
| SCHEMBL22546524 | 0.80 | KMT2A (0.61) | KMT2AL3MBTL1KDM1AMAOBCA12 | |
| SCHEMBL4266530 | 0.80 | KMT2A (0.58) | KMT2AL3MBTL1KDM1AMAOBCA12 | |
| SCHEMBL19569627 | 0.78 | KMT2A (0.62) | KMT2AL3MBTL1KDM1AMAOBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091438-A1 | CHROMANE AMIDINE MONOBACTAM ANTIBIOTICS | MERCK SHARP & DOHME LLC (US) | 2023-05-25 | — | — | WO | disclosed |