Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 5/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.32 |
| ▸ | IRAK3 | Q9Y616 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23134694 | 0.86 | IRAK1 (0.40) | CRBNDDB1IRAK1IRAK3ADORA2A | |
| SCHEMBL23134596 | 0.72 | CRBN (0.58) | CRBNDDB1IRAK1IRAK3AR | |
| SCHEMBL25691426 | 0.71 | CRBN (0.47) | CRBNDDB1IRAK1IRAK3AR | |
| SCHEMBL22692241 | 0.70 | CRBN (0.43) | CRBNDDB1IRAK1IRAK3ESR1 | |
| SCHEMBL25059028 | 0.69 | CRBN (0.56) | CRBNDDB1ESR1AR | |
| SCHEMBL23117863 | 0.69 | CRBN (0.57) | CRBNDDB1ESR1 | |
| SCHEMBL29821907 | 0.69 | CRBN (0.57) | CRBNDDB1ESR1 | |
| SCHEMBL23117862 | 0.69 | CRBN (0.57) | CRBNDDB1ESR1 | |
| SCHEMBL25815259 | 0.69 | CRBN (0.43) | CRBNDDB1ESR1 | |
| SCHEMBL20046716 | 0.69 | CRBN (0.41) | CRBNDDB1IRAK1IRAK3ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230150973-A1 | NOVEL UREAS HAVING ANDROGEN RECEPTOR DEGRADATION ACTIVITY AND USES THEREOF | ACCUTAR BIOTECHNOLOGY INC. (US) | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150973-A1 | NOVEL UREAS HAVING ANDROGEN RECEPTOR DEGRADATION ACTIVITY AND USES THEREOF | AR, UTS2R, ESRRA | CRBN 1041/4885DDB1 1112/4885IRAK1 2770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.