⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13233128 | 1.00 | — | — | |
| SCHEMBL23111100 | 1.00 | — | — | |
| Hydrazine SCHEMBL4071849 | 0.92 | — | — | |
| SCHEMBL12660772 | 0.72 | — | — | |
| SCHEMBL24950435 | 0.67 | — | — | |
| SCHEMBL13887187 | 0.66 | — | — | |
| SCHEMBL12324433 | 0.66 | — | — | |
| SCHEMBL17755530 | 0.65 | — | — | |
| SCHEMBL1179645 | 0.65 | — | — | |
| SCHEMBL10935132 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4180424-A1 | SUBSTITUTED PYRAZOLES AS HUMAN PLASMA KALLIKREIN INHIBITORS | BioCryst Pharmaceuticals, Inc. (US) | 2023-05-17 | — | — | EP | disclosed |
| US-20220145339-A1 | METHOD FOR PREPARATION OF PRIMARY AMINE COMPOUNDS | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2022-05-12 | — | — | US | disclosed |
| EP-3896065-A1 | 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLE DERIVATIVES AS PESTICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2021-10-20 | — | — | EP | disclosed |
| EP-3896066-A2 | 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLE DERIVATIVES AS PESTICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2021-10-20 | — | — | EP | disclosed |
| US-20210139480-A1 | HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-05-13 | — | — | US | disclosed |
| US-10986840-B2 | 2-(het)aryl-substituted fused heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2021-04-27 | — | — | US | disclosed |
| EP-3356362-B1 | 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLIC DERIVATIVES USEFUL AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2021-02-03 | — | — | EP | disclosed |
| US-10745398-B2 | 2-(het)aryl-substituted fused heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-08-18 | — | — | US | disclosed |
| EP-3680238-A1 | SUBSTITUTED N-(3-(PYRIMIDIN-4-YL)PHENYL)ACRYLAMIDE ANALOGS AS TYROSINE RECEPTOR KINASE BTK INHIBITORS | University of Utah Research Foundation (US) | 2020-07-15 | — | — | EP | disclosed |
| WO-2020120420-A1 | METHOD FOR PREPARATION OF PRIMARY AMINE COMPOUNDS | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2020-06-18 | — | — | WO | disclosed |
| US-20070049495-A1 | Ethylene derivatives and pesticides containing said derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2007-03-01 | — | — | US | disclosed |
| EP-1757607-A1 | N5-substituted benzo¬2,3|azepino¬4,5-b|indol-6-ones for treating tropical diseases | Molisa GmbH (DE) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005023818-A2 | HETEROBICYCLIC COMPOUNDS AS PHARMACEUTICALLY ACTIVE AGENTS | GPC BIOTECH AG (DE) | 2005-03-17 | — | — | WO | disclosed |
| EP-0290991-B1 | PROCESS FOR THE PRODUCTION OF PYRAZOLES | BASF Aktiengesellschaft (DE) | 1992-07-29 | — | — | EP | disclosed |
| EP-0237762-B1 | PROCESS FOR THE PREPARATION OF PYRAZOLES | BASF Aktiengesellschaft (DE) | 1989-06-07 | — | — | EP | disclosed |
| EP-0290991-A1 | Process for the production of pyrazoles | BASF Aktiengesellschaft (DE) | 1988-11-17 | — | — | EP | disclosed |
| US-4702803-A | Preparation of pyrazoles | BASF AKTIENGESELLSCHAFT (DE) | 1987-10-27 | — | — | US | disclosed |
| EP-0162247-B1 | PROCESS FOR THE PREPARATION OF PYRAZOLES | BASF Aktiengesellschaft (DE) | 1987-08-26 | — | — | EP | disclosed |
| EP-0162247-A1 | Process for the preparation of pyrazoles | BASF Aktiengesellschaft (DE) | 1985-11-27 | — | — | EP | disclosed |
| EP-0088963-A1 | Process for the preparation of pyrazoles by catalytic dehydrogenation of pyrazolines | BASF Aktiengesellschaft (DE) | 1983-09-21 | — | — | EP | disclosed |