⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5483732 | 0.78 | — | — | |
| SCHEMBL18804414 | 0.72 | — | — | |
| SCHEMBL27932388 | 0.72 | TSHR (0.33) | — | |
| SCHEMBL23843388 | 0.72 | — | — | |
| SCHEMBL1106405 | 0.69 | — | — | |
| SCHEMBL2273304 | 0.69 | TSHR (0.30) | — | |
| SCHEMBL17614705 | 0.67 | — | — | |
| SCHEMBL18804377 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL23933731 | 0.67 | HTT (0.32) | — | |
| SCHEMBL830542 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230190940-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2023-06-22 | — | — | US | disclosed |