Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 9/20 | 0.72 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4509812 | 0.84 | HRH4 (1.00) | HRH4CHRNB2CHRNA4 | |
| SCHEMBL4509806 | 0.84 | HRH4 (1.00) | HRH4CHRNB2CHRNA4 | |
| SCHEMBL604589 | 0.78 | HRH4 (0.69) | HRH4MAOBHTR6 | |
| SCHEMBL604590 | 0.78 | HRH4 (0.69) | HRH4MAOBHTR6 | |
| SCHEMBL12193809 | 0.78 | HRH4 (0.69) | HRH4MAOBHTR6 | |
| Trifluoroacetic Acid SCHEMBL2495245 | 0.77 | HRH4 (0.83) | HRH4 | |
| Trifluoroacetic Acid SCHEMBL2495248 | 0.77 | HRH4 (0.83) | HRH4 | |
| SCHEMBL605334 | 0.76 | HRH4 (1.00) | HRH4 | |
| SCHEMBL605333 | 0.76 | HRH4 (1.00) | HRH4 | |
| SCHEMBL4496887 | 0.76 | HRH4 (1.00) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382013-A1 | SELECTIVE HISTAMINE H4 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF VESTIBULAR DISORDERS. | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2011-11-02 | — | — | EP | disclosed |
| WO-2010072829-A1 | SELECTIVE HISTAMINE H4 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF VESTIBULAR DISORDERS. | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2010-07-01 | — | — | WO | disclosed |